Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528998 | 0.94 | CYP2C19 (0.42) | CYP2C19HIF1ATAAR1SIGMAR1LMNA | |
| SCHEMBL6353040 | 0.92 | CYP2C19 (0.41) | CYP2C19HIF1ATAAR1SIGMAR1LMNA | |
| SCHEMBL5523481 | 0.89 | CYP2C19 (0.43) | CYP2C19HIF1ATAAR1SIGMAR1LMNA | |
| SCHEMBL6343459 | 0.83 | CYP2C19 (0.41) | CYP2C19HIF1A | |
| SCHEMBL6344497 | 0.83 | CYP2C19 (0.41) | CYP2C19HIF1ATAAR1SIGMAR1LMNA | |
| SCHEMBL6348374 | 0.83 | CYP2C19 (0.41) | CYP2C19HIF1ATAAR1SIGMAR1CNR2 | |
| SCHEMBL6352901 | 0.82 | CYP2C19 (0.40) | CYP2C19HIF1A | |
| SCHEMBL6346489 | 0.81 | CYP2C19 (0.40) | CYP2C19HIF1ATAAR1SIGMAR1LMNA | |
| SCHEMBL6351858 | 0.81 | CYP2C19 (0.40) | CYP2C19HIF1ATAAR1SIGMAR1CNR2 | |
| SCHEMBL6272988 | 0.81 | CYP2C19 (0.37) | CYP2C19HIF1ATAAR1SIGMAR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539127-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017952-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |