Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.43 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620821 | 1.00 | HDAC3 (0.49) | HDAC3HDAC1HDAC2NAMPTKCNA3 | |
| SCHEMBL27620833 | 0.93 | HDAC3 (0.41) | HDAC3HDAC1HDAC2NAMPTKCNA3 | |
| SCHEMBL5497058 | 0.89 | HDAC1 (0.39) | HDAC3HDAC1HDAC2USP30KMT2A | |
| SCHEMBL5496605 | 0.89 | HDAC1 (0.39) | HDAC3HDAC1HDAC2USP30KMT2A | |
| SCHEMBL5499584 | 0.89 | HDAC1 (0.39) | HDAC3HDAC1HDAC2USP30KMT2A | |
| SCHEMBL5500964 | 0.86 | USP30 (0.51) | USP30PARP1PDE10ACA1CA2 | |
| SCHEMBL5495007 | 0.82 | TRPV1 (0.40) | USP30 | |
| SCHEMBL5493363 | 0.82 | MAPT (0.44) | NAMPTCKS1BSKP1SKP2KMT2A | |
| SCHEMBL5493346 | 0.81 | HDAC1 (0.35) | HDAC3HDAC1HDAC2CYP2C9 | |
| SCHEMBL5493786 | 0.80 | USP30 (0.42) | NAMPTUSP30PDE10ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |