Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.44 |
| ▸ | NPC1 | O15118 | 11/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829105 | 0.84 | KDM4E (0.40) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4829121 | 0.84 | KDM4E (0.40) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4554192 | 0.83 | MAPT (0.41) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4554191 | 0.82 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3486759 | 0.82 | MAPT (0.42) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3486750 | 0.82 | MAPT (0.42) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4554193 | 0.82 | MAPT (0.40) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL964306 | 0.81 | MAPT (0.39) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL964305 | 0.80 | HDAC1 (0.45) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4825696 | 0.79 | KDM4E (0.53) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | claimed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | claimed |