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Sugi Predict / Compounds / SCHEMBL6430591

SCHEMBL6430591

SCHEMBL6430591

CN(CCCc1ccccc1)CCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4975423 0.96 TRPV1 (0.72) TRPV1
SCHEMBL6644329 0.95 TRPV1 (0.72) TRPV1
SCHEMBL4975057 0.92 TRPV1 (0.73) TRPV1
SCHEMBL4973805 0.92 TRPV1 (0.72) TRPV1
SCHEMBL4974031 0.92 TRPV1 (0.74) TRPV1
SCHEMBL4975086 0.90 TRPV1 (0.70) TRPV1
SCHEMBL4974044 0.90 TRPV1 (0.74) TRPV1
SCHEMBL4971791 0.88 TRPV1 (0.79) TRPV1
SCHEMBL4974976 0.87 TRPV1 (0.77) TRPV1
SCHEMBL4974830 0.87 TRPV1 (0.70) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1471910-A2 SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS MODULATORS OF CAPSAICIN RECEPTORS NEUROGEN CORPORATION (US) 2004-11-03 — — EP claimed
WO-2003062209-A2 SUBSTITUTED QUINAZOLIN-4-YLAMINE ANALOGUES AS MODULATORS OF CAPSAICIN NEUROGEN CORPORATION (US) 2003-07-31 — — WO claimed
EP-1581225-A1 COMBINATION THERAPY FOR THE TREATMENT OF PAIN NEUROGEN CORPORATION (US) 2005-10-05 — — EP disclosed
WO-2004054582-A1 COMBINATION THERAPY FOR THE TREATMENT OF PAIN NEUROGEN CORPORATION (US) 2004-07-01 — — WO disclosed