Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 9/20 | 0.75 |
| ▸ | FLT1 | P17948 | 9/20 | 0.75 |
| ▸ | KDR | P35968 | 9/20 | 0.75 |
| ▸ | EGFR | P00533 | 7/20 | 0.75 |
| ▸ | FLT4 | P35916 | 5/20 | 0.75 |
| ▸ | EHMT2 | Q96KQ7 | 9/20 | 0.68 |
| ▸ | EHMT1 | Q9H9B1 | 9/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6434695 | 0.99 | FGFR1 (0.77) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6431410 | 0.92 | EGFR (0.78) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6430831 | 0.92 | EGFR (0.78) | FGFR1FLT1KDREGFRFLT4 | |
| Hydrochloric Acid SCHEMBL6882131 | 0.91 | EGFR (0.77) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL6431147 | 0.87 | FLT1 (0.75) | FGFR1FLT1KDREGFRFLT4 | |
| Hydrochloric Acid SCHEMBL6095874 | 0.87 | KDR (0.73) | FGFR1FLT1KDREGFRFLT4 | |
| SCHEMBL1468087 | 0.87 | FGFR1 (0.98) | FGFR1FLT1KDREGFRFLT4 | |
| Hydrochloric Acid SCHEMBL6432102 | 0.86 | FLT1 (0.73) | FGFR1FLT1KDREGFRFLT4 | |
| Hydrochloric Acid SCHEMBL27218199 | 0.86 | FGFR1 (1.00) | FGFR1FLT1KDREGFRFLT4 | |
| Hydrochloric Acid SCHEMBL1467744 | 0.85 | FGFR1 (0.98) | FGFR1FLT1KDREGFRFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929526-B1 | QINOLINE DERIVATIVES INHIBITING THE EFFECT OF GROWTH FACTORS SUCH AS VEGF | ASTRAZENECA AB (SE) | 2005-07-27 | — | — | EP | claimed |
| US-6809097-B1 | ANTIANGIOGENIC AND/OR VASCULAR PERMEABILITY | ZENECA LIMITED (GB) | 2004-10-26 | — | — | US | claimed |
| EP-0929526-B1 | QINOLINE DERIVATIVES INHIBITING THE EFFECT OF GROWTH FACTORS SUCH AS VEGF | ASTRAZENECA AB (SE) | 2005-07-27 | — | — | EP | disclosed |
| US-6809097-B1 | ANTIANGIOGENIC AND/OR VASCULAR PERMEABILITY | ZENECA LIMITED (GB) | 2004-10-26 | — | — | US | disclosed |