⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10011189 | 0.92 | — | — | |
| SCHEMBL3220985 | 0.79 | — | — | |
| SCHEMBL7779358 | 0.79 | — | — | |
| SCHEMBL27927037 | 0.79 | — | — | |
| SCHEMBL23655258 | 0.77 | TSHR (0.40) | — | |
| SCHEMBL9355012 | 0.77 | PAOX (0.50) | — | |
| SCHEMBL10370310 | 0.77 | PAOX (0.50) | — | |
| SCHEMBL17260760 | 0.77 | PAOX (0.50) | — | |
| SCHEMBL1004740 | 0.77 | TSHR (0.40) | — | |
| SCHEMBL10714171 | 0.77 | TSHR (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050020544-A1 | Bicyclic CB2 cannabinoid receptor ligands | PHARMOS CORPORATION | 2005-01-27 | — | — | US | claimed |
| US-20170283378-A1 | INDOLE DERIVATIVES FOR THE PREVENTION AND/OR TREATMENT OF DIABETES AND ASSOCIATED METABOLIC DISORDERS | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2017-10-05 | — | — | US | disclosed |
| EP-3196190-A1 | INDOLE DERIVATIVES FOR THE PREVENTION AND/OR TREATMENT OF DIABETES AND ASSOCIATED METABOLIC DISORDERS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2017-07-26 | — | — | EP | disclosed |
| US-20050020544-A1 | Bicyclic CB2 cannabinoid receptor ligands | PHARMOS CORPORATION | 2005-01-27 | — | — | US | disclosed |