Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 11/20 | 0.42 |
| ▸ | CDK8 | P49336 | 11/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833494 | 0.86 | CCNC (0.43) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4833485 | 0.86 | CCNC (0.43) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831386 | 0.85 | EGFR (0.48) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831378 | 0.85 | EGFR (0.48) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831468 | 0.82 | CCNC (0.49) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831457 | 0.82 | CCNC (0.49) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831578 | 0.82 | CCNC (0.42) | CCNCCDK8CDK19 | |
| SCHEMBL4831592 | 0.82 | CCNC (0.42) | CCNCCDK8CDK19 | |
| SCHEMBL4826317 | 0.82 | CCNC (0.49) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4826330 | 0.82 | CCNC (0.49) | CCNCCDK8CDK19MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |