Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 8/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 10/20 | 0.37 |
| ▸ | CTSK | P43235 | 9/20 | 0.37 |
| ▸ | CTSL | P07711 | 9/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642123 | 0.90 | F2R (0.53) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL643018 | 0.84 | F2R (0.52) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL3972756 | 0.83 | F2R (0.55) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL641944 | 0.81 | F2R (0.51) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL10234891 | 0.81 | F2R (0.51) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL641180 | 0.78 | F2R (0.61) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL12720313 | 0.78 | F2R (0.53) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL642183 | 0.78 | F2R (0.61) | F2RCNR1TMEM97CTSSCTSK | |
| SCHEMBL643047 | 0.76 | F2R (0.64) | F2RCNR1TMEM97TACR1EPHX2 | |
| SCHEMBL11996162 | 0.76 | F2R (0.59) | F2RCNR1TMEM97CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119663-B2 | Heteroaryl-substituted piperidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-02-21 | — | — | US | disclosed |
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2227466-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |