Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 7/20 | 0.43 |
| ▸ | CNR2 | P34972 | 6/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432351 | 0.89 | MEN1 (0.52) | MAPK9MAPK10MEN1KMT2AUSP5 | |
| SCHEMBL6431561 | 0.86 | KMT2A (0.54) | MAPK9MAPK10MEN1KMT2AUSP5 | |
| SCHEMBL2420054 | 0.85 | MAPK9 (0.62) | MAPK9MAPK10MEN1KMT2ACNR1 | |
| SCHEMBL2426238 | 0.85 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2ACNR1 | |
| SCHEMBL2427768 | 0.84 | MAPK9 (0.61) | MAPK9MAPK10MEN1KMT2ACNR1 | |
| SCHEMBL6431659 | 0.84 | CNR1 (0.43) | MAPK9MAPK10CNR1CNR2USP5 | |
| SCHEMBL1518791 | 0.84 | MAPK9 (0.64) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL2424677 | 0.84 | MAPK9 (0.58) | MAPK9MAPK10MEN1KMT2ACNR1 | |
| SCHEMBL2424782 | 0.83 | MAPK9 (0.58) | MAPK9MAPK10MEN1KMT2ACNR1 | |
| SCHEMBL2423120 | 0.83 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | claimed |