Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431975 | 0.86 | SRD5A1 (0.34) | SRD5A1SRD5A2 | |
| SCHEMBL6434024 | 0.82 | SRD5A1 (0.35) | SRD5A1SRD5A2 | |
| SCHEMBL6431481 | 0.78 | SRD5A2 (0.38) | SRD5A1SRD5A2 | |
| SCHEMBL6431812 | 0.77 | SRD5A2 (0.42) | SRD5A1SRD5A2 | |
| SCHEMBL6431560 | 0.77 | SRD5A1 (0.32) | SRD5A1 | |
| SCHEMBL6432809 | 0.74 | SRD5A1 (0.36) | SRD5A1 | |
| SCHEMBL6433922 | 0.74 | — | — | |
| SCHEMBL6430847 | 0.74 | SRD5A2 (0.43) | SRD5A1SRD5A2 | |
| SCHEMBL6432295 | 0.67 | SRD5A1 (0.37) | SRD5A1 | |
| SCHEMBL6431351 | 0.66 | SRD5A2 (0.40) | SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962925-B1 | Benzo(C)quinolizine derivatives and their use as 5α-reductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-11-08 | — | — | US | claimed |
| EP-1066284-B1 | BENZO(C)QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2005-08-31 | — | — | EP | claimed |
| EP-0926148-A1 | Benzo (C)quinolizine derivatives, their preparation and use as 5-alphareductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-06-30 | — | — | EP | claimed |
| EP-1066284-B1 | BENZO(C)QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2005-08-31 | — | — | EP | disclosed |
| EP-1066284-A1 | BENZO C]QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999033828-A1 | BENZO[C]QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-07-08 | — | — | WO | disclosed |
| EP-0926148-A1 | Benzo (C)quinolizine derivatives, their preparation and use as 5-alphareductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-06-30 | — | — | EP | disclosed |