Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 19/20 | 0.76 |
| ▸ | FYN | P06241 | 2/20 | 0.72 |
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 7/20 | 0.54 |
| ▸ | TEK | Q02763 | 6/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465467 | 0.91 | LCK (0.82) | LCKFYNBTKSRCTEK | |
| SCHEMBL4828202 | 0.90 | LCK (0.85) | LCKFYNBTKSRCTEK | |
| SCHEMBL4820398 | 0.90 | LCK (0.84) | LCKFYNBTKSRCTEK | |
| SCHEMBL6430928 | 0.88 | LCK (0.86) | LCKFYNBTKSRCTEK | |
| SCHEMBL4826601 | 0.87 | LCK (0.82) | LCKFYNBTKSRCTEK | |
| SCHEMBL4821401 | 0.87 | LCK (0.86) | LCKFYNBTKSRCTEK | |
| SCHEMBL6433364 | 0.87 | LCK (0.84) | LCKFYNBTKSRCTEK | |
| SCHEMBL6430960 | 0.87 | LCK (0.80) | LCKFYNBTKSRCTEK | |
| SCHEMBL6430474 | 0.87 | LCK (1.00) | LCKFYNBTKSRCTEK | |
| SCHEMBL6431078 | 0.86 | LCK (0.83) | LCKFYNBTKSRCTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921763-B2 | Pyrazolopyrimidines as therapeutic agents | ABBOTT LABORATORIES (US) | 2005-07-26 | — | — | US | disclosed |