SCHEMBL6432824

SCHEMBL6432824

CCCCC=CCCCCCCCCCl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
ALDH1A1 P00352 1/20 0.60
FAAH O00519 5/20 0.52
TRPV1 Q8NER1 1/20 0.52
F7 P08709 2/20 0.50
F3 P13726 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
CYP1A2 P05177 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C19 P33261 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
KMT2A Q03164 2/20 0.45
GMNN O75496 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10713908 1.00 TSHR (0.60) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL6437912 1.00 TSHR (0.60) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL31160376 1.00 TSHR (0.60) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL14245073 1.00 TSHR (0.60) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL5250474 1.00 TSHR (0.60) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL31160401 1.00 TSHR (0.60) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL14245076 1.00 TSHR (0.60) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL27296457 0.97 TSHR (0.65) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL1030040 0.97 TSHR (0.55) TSHRALDH1A1FAAHTRPV1F7
SCHEMBL1030039 0.97 TSHR (0.55) TSHRALDH1A1FAAHTRPV1F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1230207-B1 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS PEDERSON RICHARD L (US) 2005-06-22 EP claimed
US-6696597-B2 CROSS-METATHESIZING A TERMINAL OLEFIN AND INTERNAL OLEFIN IN PRESENCE OF CATALYST, TO FORM METATHESIS PRODUCT AND A SIDE PRODUCT; APPLYING CONDITIONS OF SUFFICIENTLY HIGH TEMPERATURE AND/OR LOW PRESSURE TO EVAPORTE SIDE PRODUCT TILLIECHEM, INC. 2004-02-24 US claimed
EP-1230207-A2 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS Pederson, Richard L. (US) 2002-08-14 EP claimed
US-20020022741-A1 Metathesis syntheses of pheromones or their components MATERIA, INC. 2002-02-21 US claimed
WO-2001036368-A2 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS PEDERSON RICHARD L (US) 2001-05-25 WO claimed
CN-106083579-A By olefin metathesis by the method for internal olefin synthesis terminal olefin 埃莱文斯可更新科学公司 2016-11-09 CN disclosed
CN-100528829-C Metathesis synthesis of pheromones or components thereof R L PEDERSON R H GRUBBS (US) 2009-08-19 CN disclosed
EP-1230207-B1 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS PEDERSON RICHARD L (US) 2005-06-22 EP disclosed
US-6696597-B2 CROSS-METATHESIZING A TERMINAL OLEFIN AND INTERNAL OLEFIN IN PRESENCE OF CATALYST, TO FORM METATHESIS PRODUCT AND A SIDE PRODUCT; APPLYING CONDITIONS OF SUFFICIENTLY HIGH TEMPERATURE AND/OR LOW PRESSURE TO EVAPORTE SIDE PRODUCT TILLIECHEM, INC. 2004-02-24 US disclosed
CN-1423629-A Metathesis synthesis of pheromones or components thereof PEDERSON R L (US) 2003-06-11 CN disclosed
EP-1230207-A2 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS Pederson, Richard L. (US) 2002-08-14 EP disclosed
US-20020022741-A1 Metathesis syntheses of pheromones or their components MATERIA, INC. 2002-02-21 US disclosed
WO-2001036368-A2 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS PEDERSON RICHARD L (US) 2001-05-25 WO disclosed
US-6215019-B1 SELF-METATHESIZING 1-HEXENE USING GRUBBS' CATALYST; CROSS-METATHESIZING PRODUCT WITH ALCOHOL OR ACETATE-PROTECTED HEXENE TILLIECHEM, INC. 2001-04-10 US disclosed