Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433061 | 1.00 | CA12 (0.37) | CA12CA1CA9ESR2PREP | |
| SCHEMBL6499014 | 0.91 | CA12 (0.38) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6434920 | 0.85 | CA12 (0.37) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6434515 | 0.84 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6433944 | 0.84 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6433948 | 0.84 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6499011 | 0.84 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6804163 | 0.82 | CA12 (0.40) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL5360778 | 0.81 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL5360774 | 0.81 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |