Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857644 | 1.00 | TSHR (0.63) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL4638766 | 0.92 | TSHR (0.55) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL10649958 | 0.90 | TSHR (0.62) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL28132641 | 0.90 | TSHR (0.57) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL730240 | 0.90 | TSHR (0.57) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL13109807 | 0.90 | TSHR (0.57) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL22346068 | 0.90 | TSHR (0.57) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL10390171 | 0.89 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL19294802 | 0.89 | TSHR (0.52) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL3678515 | 0.88 | TSHR (0.60) | TSHRTHRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924437-A1 | RESIN COMPOSITIONS AND METHODS OF PRODUCTION | Momentive Performance Materials Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020167507-A1 | RESIN COMPOSITIONS AND METHODS OF PRODUCTION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2020-08-20 | — | — | WO | disclosed |
| EP-1326901-B1 | ACYLPHOSPHINE OXIDE PHOTOINITIATORS IN METHACRYLATE CASTING RESINS | CIBA SC HOLDING AG (CH) | 2005-06-08 | — | — | EP | disclosed |
| US-20030164580-A1 | Acylphosphine oxide photoinitiators in methacrylate casting resins | CIBA SPECIALTY CHEMICALS CORP. | 2003-09-04 | — | — | US | disclosed |