SCHEMBL6433800

SCHEMBL6433800

COC(C(=O)O)C(CC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.37
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
MMP13 P45452 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.35
PGD P52209 1/20 0.32
FOLH1 Q04609 2/20 0.32
ALOX15 P16050 1/20 0.31
MAPT P10636 1/20 0.31
MMP12 P39900 1/20 0.31
GABRR1 P24046 2/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL3736484 0.94 TDP1 (0.50) TDP1SLC1A3SLC1A2SLC1A1SMN1; SMN2
1,4-Butanediol SCHEMBL3731758 0.90 TDP1 (0.46) TDP1SLC1A3SLC1A2SLC1A1SMN1; SMN2
Propylene Glycol SCHEMBL3728467 0.89 TDP1 (0.45) TDP1SLC1A3SLC1A2SLC1A1SMN1; SMN2
Di(Hydroxyethyl)Ether SCHEMBL3731903 0.87 TDP1 (0.43) TDP1SLC1A3SLC1A2SLC1A1MMP1
Tetraethylene Glycol SCHEMBL3739063 0.86 TDP1 (0.42) TDP1SLC1A3SLC1A2SLC1A1MAPT
Triethylene Glycol SCHEMBL3734027 0.86 TDP1 (0.42) TDP1SLC1A3SLC1A2SLC1A1MAPT
SCHEMBL3727002 0.83 TDP1 (0.39) TDP1SLC1A3SLC1A2SLC1A1MAPT
SCHEMBL3731852 0.83 TDP1 (0.39) TDP1SLC1A3SLC1A2SLC1A1MAPT
SCHEMBL6668479 0.83 SLC1A1 (0.43) TDP1SLC1A3SLC1A2SLC1A1MMP1
SCHEMBL3742010 0.79 TDP1 (0.36) TDP1SLC1A3SLC1A2SLC1A1PGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4081420-A Carboxymethyloxysuccinic acid esters as plastic plasticizers LEVER BROTHERS COMPANY (US) 1978-03-28 US claimed
CN-110179775-A Application of the crystal violet in Killing Mycobacterium Tuberculosis infection 天津国际生物医药联合研究院 2019-08-30 CN disclosed
CN-104795595-A Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES 2015-07-22 CN disclosed
CN-102498605-B Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES 2015-05-20 CN disclosed
EP-1334180-A4 ISOCITRATE DEHYDROGENASE, GENE THEREOF, AND USE OF THE SAME IN THE TREATMENT OF OBESITY, HYPERLIPIDEMIA, AND FATTY LIVER IN LIPID BIOSYNTHESIS TG BIOTECH INC (KR) 2005-04-06 EP disclosed
US-20040214270-A1 Isocitrate dehydrogenase, gene thereof, and use of the same in the treatment of obesity, hyperlipidemia, and fattly liver in lipid biosynthesis TG BIOTECH, INC. (KR) 2004-10-28 US disclosed
EP-0831767-B1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 2004-09-22 EP disclosed
CN-1524122-A Isocitrate dehydrogenase, gene thereof, and use of the same in the treatment of obesity, hyperlipidemia, and fatty liver in lipid biosynthesis TG生命工学株式会社 2004-08-25 CN disclosed
EP-1334180-A1 ISOCITRATE DEHYDROGENASE, GENE THEREOF, AND USE OF THE SAME IN THE TREATMENT OF OBESITY, HYPERLIPIDEMIA, AND FATTY LIVER IN LIPID BIOSYNTHESIS TG Biotech, Inc. (KR) 2003-08-13 EP disclosed
WO-2002033063-A1 ISOCITRATE DEHYDROGENASE, GENE THEREOF, AND USE OF THE SAME IN THE TREATMENT OF OBESITY, HYPERLIPIDEMIA, AND FATTY LIVER IN LIPID BIOSYNTHESIS TG BIOTECH, INC. (KR) 2002-04-25 WO disclosed
EP-0831767-A4 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 2000-05-17 EP disclosed
EP-0831767-A1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING Yu, Ruey J., Dr. (US) 1998-04-01 EP disclosed
US-5686489-A TOPICALLY APPLIED TO INDUCE GLYCOSAMINOGLYCAN, PROTEOGLYCAN, COLLAGEN AND ELASTIN BIOSYNTHESIS; WRINKLE RESISTANCE TRISTRATA TECHNOLOGY, INC. (US) 1997-11-11 US disclosed
WO-1996040047-A1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 1996-12-19 WO disclosed
US-4081420-A Carboxymethyloxysuccinic acid esters as plastic plasticizers LEVER BROTHERS COMPANY (US) 1978-03-28 US disclosed
US-3996150-A DETERGENT WITH SURFACTANT, BUILDER LEVER BROTHERS COMPANY (US) 1976-12-07 US disclosed
US-3943165-A DETERGENT SOLVENTS, PLASTICIZERS LEVER BROTHERS COMPANY (US) 1976-03-09 US disclosed