Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428331 | 0.95 | KMT2A (0.51) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL2425516 | 0.94 | MEN1 (0.54) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL6432690 | 0.94 | MEN1 (0.52) | MEN1KMT2AMAPK9MAPK10POLB | |
| SCHEMBL2424613 | 0.93 | MEN1 (0.47) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL2421112 | 0.92 | KMT2A (0.51) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL2423246 | 0.92 | MEN1 (0.46) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL2422148 | 0.92 | KMT2A (0.50) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL2428248 | 0.92 | MEN1 (0.47) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL2421192 | 0.91 | MEN1 (0.49) | MEN1KMT2AG6PDSIRT2MAPK9 | |
| SCHEMBL2423188 | 0.90 | KMT2A (0.48) | MEN1KMT2AG6PDSIRT2MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | claimed |