Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylic Acid SCHEMBL27825208 | 0.98 | CYP2C9 (0.53) | CYP2C9CYP2D6LMNAMEN1HRH1 | |
| Benzylic Acid SCHEMBL7066 | 0.83 | CYP2C9 (0.74) | CYP2C9CYP2D6LMNAKMT2AKEAP1 | |
| Benzylic Acid SCHEMBL9568239 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A | |
| Benzylic Acid SCHEMBL1681667 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A | |
| Benzylic Acid SCHEMBL868225 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A | |
| Benzylic Acid SCHEMBL9181980 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A | |
| Benzylic Acid SCHEMBL5705762 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A | |
| Benzylic Acid SCHEMBL11049826 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A | |
| Benzylic Acid SCHEMBL20957595 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A | |
| Benzylic Acid SCHEMBL1680669 | 0.81 | CYP2C9 (0.71) | CYP2C9CYP2D6LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589959-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | Dynogen Pharmaceuticals Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004066990-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |