Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431211 | 0.81 | SRD5A1 (0.32) | SRD5A1 | |
| SCHEMBL6431301 | 0.75 | SRD5A1 (0.38) | SRD5A1 | |
| SCHEMBL6431821 | 0.74 | SRD5A1 (0.34) | SRD5A1 | |
| SCHEMBL6431337 | 0.73 | SRD5A2 (0.39) | SRD5A1 | |
| SCHEMBL6435587 | 0.68 | SRD5A1 (0.39) | SRD5A1 | |
| SCHEMBL6435646 | 0.66 | SRD5A1 (0.33) | SRD5A1 | |
| SCHEMBL6431560 | 0.64 | SRD5A1 (0.32) | SRD5A1 | |
| SCHEMBL6430872 | 0.61 | SRD5A2 (0.46) | SRD5A1 | |
| SCHEMBL6436318 | 0.59 | SRD5A1 (0.38) | SRD5A1 | |
| SCHEMBL7888454 | 0.59 | SRD5A1 (0.38) | SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6962925-B1 | Benzo(C)quinolizine derivatives and their use as 5α-reductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-11-08 | — | — | US | claimed |
| EP-1066284-B1 | BENZO(C)QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2005-08-31 | — | — | EP | claimed |
| EP-0926148-A1 | Benzo (C)quinolizine derivatives, their preparation and use as 5-alphareductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-06-30 | — | — | EP | claimed |
| US-6962925-B1 | Benzo(C)quinolizine derivatives and their use as 5α-reductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-11-08 | — | — | US | disclosed |
| EP-1066284-B1 | BENZO(C)QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2005-08-31 | — | — | EP | disclosed |
| EP-1066284-A1 | BENZO C]QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999033828-A1 | BENZO[C]QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-07-08 | — | — | WO | disclosed |
| EP-0926148-A1 | Benzo (C)quinolizine derivatives, their preparation and use as 5-alphareductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-06-30 | — | — | EP | disclosed |