Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641044 | 0.93 | GRM5 (0.56) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL10234679 | 0.91 | CNR1 (0.59) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL10234683 | 0.91 | CNR1 (0.55) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL10234676 | 0.90 | GRM5 (0.56) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL643138 | 0.90 | GRM5 (0.53) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL3968964 | 0.90 | GRM5 (0.53) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL10233885 | 0.90 | GRM5 (0.70) | GRM5 | |
| SCHEMBL3968968 | 0.89 | GRM5 (0.52) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL1580656 | 0.89 | GRM5 (0.52) | GRM5CNR1F2RTMEM97L3MBTL1 | |
| SCHEMBL642333 | 0.89 | GRM5 (0.52) | GRM5CNR1F2RTMEM97L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120214788-A1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-08-23 | — | — | US | disclosed |
| US-8119663-B2 | Heteroaryl-substituted piperidines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090306139-A1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER HEALTHCARE AG (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306139-A1 | HETEROARYL-SUBSTITUTED PIPERIDINES | VHL, PIGO, PLIN3 | GRM5 1833/4885CNR1 454/4885F2R 698/4885 |
| US-20120214788-A1 | HETEROARYL-SUBSTITUTED PIPERIDINES | VHL, PIGO, PLIN3 | GRM5 1833/4885CNR1 454/4885F2R 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.