Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.69 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1347334 | 0.84 | MAOB (0.76) | MAOBMAOANR4A2PARP10GSK3B | |
| SCHEMBL29464145 | 0.84 | MAOB (0.76) | MAOBMAOANR4A2PARP10GSK3B | |
| SCHEMBL27521276 | 0.83 | MAOB (0.77) | MAOBMAOANR4A2PARP10 | |
| SCHEMBL992837 | 0.82 | MAOB (1.00) | MAOBNR4A2PARP10 | |
| SCHEMBL28115363 | 0.81 | PTPN1 (0.49) | MAOBMAOA | |
| SCHEMBL28115794 | 0.81 | MAOB (0.69) | MAOBMAOANR4A2 | |
| SCHEMBL28488896 | 0.81 | MAOB (0.73) | MAOBMAOANR4A2PARP10SCN9A | |
| SCHEMBL29817726 | 0.81 | MAOB (0.73) | MAOBMAOANR4A2PARP10SCN9A | |
| Hydrochloric Acid SCHEMBL21313331 | 0.81 | MAOB (1.00) | MAOBNR4A2PARP10 | |
| SCHEMBL4228330 | 0.81 | MAOB (0.73) | MAOBMAOANR4A2PARP10SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1523469-A1 | CINNAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004007429-A1 | CINNAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-22 | — | — | WO | disclosed |