SCHEMBL6436060

SCHEMBL6436060

CCCCCCCCc1ccc(O)c(O)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.73
ALOX5 P09917 2/20 0.59
MEN1 O00255 1/20 0.59
TP53 P04637 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAPT P10636 1/20 0.59
ALOX15 P16050 1/20 0.59
TSHR P16473 1/20 0.59
HTT P42858 1/20 0.59
KMT2A Q03164 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ELANE P08246 2/20 0.50
CTSG P08311 2/20 0.50
PTGS2 P35354 1/20 0.50
BID P55957 3/20 0.47
MCL1 Q07820 3/20 0.47
BCL2L1 Q07817 2/20 0.47
BAK1 Q16611 2/20 0.47
KAT8 Q9H7Z6 2/20 0.47
PPARG P37231 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10607947 1.00 TYR (0.73) TYRALOX5MEN1TP53CYP3A4
SCHEMBL10608049 1.00 TYR (0.73) TYRALOX5MEN1TP53CYP3A4
SCHEMBL10608016 1.00 TYR (0.73) TYRALOX5MEN1TP53CYP3A4
SCHEMBL6343723 0.98 TYR (0.70) TYRALOX5MEN1TP53CYP3A4
SCHEMBL2382145 0.92 TYR (0.61) TYRALOX5MEN1TP53CYP3A4
SCHEMBL5677194 0.89 TYR (0.68) TYRALOX5MEN1TP53CYP3A4
SCHEMBL5678235 0.87 TYR (0.66) TYRALOX5MEN1TP53CYP3A4
SCHEMBL5677935 0.85 TYR (0.63) TYRALOX5MEN1TP53CYP3A4
SCHEMBL11698491 0.85 TYR (0.69) TYRALOX5MEN1TP53CYP3A4
SCHEMBL1208346 0.85 TYR (0.69) TYRALOX5MEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2709977-B1 USE OF BENZOTROPOLONE DERIVATIVES AS PHOTOSTABILIZER AND ANTIOXIDANT FOR STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS. BASF SE (DE) 2018-09-05 EP disclosed
US-9663442-B2 Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives BASF SE (DE) 2017-05-30 US disclosed
US-20150353470-A1 STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES BASF SE (DE) 2015-12-10 US disclosed
US-8784853-B2 Stabilization of household, body-care and food products by using benzotropolone containing plant extracts and/or related benzotropolone derivatives BASF SE (DE) 2014-07-22 US disclosed
EP-2709977-A2 USE OF BENZOTROPOLONE DERIVATIVES AS PHOTOSTABILIZER AND ANTIOXIDANT FOR STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS. BASF SE (DE) 2014-03-26 EP disclosed
US-20120230925-A1 STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES BASF SE (DE) 2012-09-13 US disclosed
EP-1141071-B1 HIGH STRENGTH EPOXY ADHESIVE AND USES THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2005-09-14 EP disclosed
US-6800157-B2 CHAIN EXTENDER, A CATALYST, A REACTIVE EPOXY RESIN, AND A POLYMERIC TOUGHNER FORMS A THERMALLY CURABLE STRUCTURAL ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY 2004-10-05 US disclosed
US-6486256-B1 Composition of epoxy resin, chain extender and polymeric toughener with separate base catalyst 3M INNOVATIVE PROPERTIES COMPANY 2002-11-26 US disclosed
EP-0069195-B1 STABILIZED ETHYLENE/CHLOROTRIFLUOROETHYLENE COPOLYMER COMPOSITION Ausimont, U.S.A., Inc. (US) 1988-08-24 EP disclosed
US-4539354-A PHOSPHITE DERIVATIVE OF A PHENOL, A GROUP II METAL CARBOXYLATE ANDAN ESTER OF A POLYOL ALLIED CORPORATION (US) 1985-09-03 US disclosed
EP-0069195-A2 Stabilized ethylene/chlorotrifluoroethylene copolymer composition Ausimont, U.S.A., Inc. (US) 1983-01-12 EP disclosed
US-4060513-A BENZOPHENONE U.V. STABILIZERSPOLYOLEFIN CINCINNATI MILACRON, INC. (US) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120230925-A1 STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES CBR3, CBR1, CYP8B1 TYR 537/4885ALOX5 123/4885MEN1 3702/4885
US-20150353470-A1 STABILIZATION OF HOUSEHOLD, BODY-CARE AND FOOD PRODUCTS BY USING BENZOTROPOLONE CONTAINING PLANT EXTRACTS AND/OR RELATED BENZOTROPOLONE DERIVATIVES CBR3, CBR1, CYP8B1 TYR 513/4885ALOX5 110/4885MEN1 3594/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.