Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 14/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.39 |
| ▸ | PTPRC | P08575 | 3/20 | 0.35 |
| ▸ | PTPRB | P23467 | 2/20 | 0.35 |
| ▸ | PTPRE | P23469 | 2/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | PTPRA | P18433 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415894 | 0.90 | PTPN1 (0.48) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6419481 | 0.84 | PTPN1 (0.47) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6415875 | 0.83 | PTPN1 (0.50) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6416126 | 0.76 | PTPN1 (0.38) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL7029267 | 0.75 | KMT2A (0.33) | PTPN1KMT2APOLBCASP6MEN1 | |
| SCHEMBL6416111 | 0.71 | PTPN1 (0.45) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6414118 | 0.71 | PTPN1 (0.48) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6416872 | 0.70 | PTPN1 (0.44) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL7850173 | 0.65 | PTPN1 (0.78) | PTPN1PTPN2PTPRCPTPRBPTPRE | |
| SCHEMBL6316048 | 0.64 | KDM4E (0.46) | PTPN1PTPN2PTPRCPTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404682-B1 | METHOD OF INHIBITING PTP 1B AND/OR T-CELL PTP AND/OR OTHER PTPASES WITH AN ASP RESIDUE AT POSITION 48 | NOVO NORDISK AS (DK) | 2005-09-14 | — | — | EP | disclosed |