SCHEMBL6436724

SCHEMBL6436724

Clc1[c]c2ccc3ccccc3c2cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.50
CYP2A6 P11509 4/20 0.48
HSD17B10 Q99714 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP3A4 P08684 3/20 0.43
MAPT P10636 2/20 0.43
MAPK1 P28482 2/20 0.43
LMNA P02545 1/20 0.43
APEX1 P27695 1/20 0.43
PMP22 Q01453 1/20 0.43
PAX8 Q06710 1/20 0.42
HIF1A Q16665 2/20 0.41
CYP1B1 Q16678 1/20 0.41
CYP1A2 P05177 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.36
RAB9A P51151 2/20 0.34
ERBB2 P04626 1/20 0.34
FYN P06241 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48950 0.76 CYP2A6 (0.37) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL8693942 0.76 HPRT1 (0.50) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL3112841 0.76 HPRT1 (0.50) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL1986723 0.76 HPRT1 (0.50) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL2139310 0.76 HPRT1 (0.50) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL8571906 0.76 HPRT1 (0.50) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL1392239 0.76
SCHEMBL18317258 0.74 HPRT1 (0.54) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL22127731 0.74 HPRT1 (0.54) HPRT1CYP2A6HSD17B10ALDH1A1TSHR
SCHEMBL18317617 0.74 HPRT1 (0.54) HPRT1CYP2A6HSD17B10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1454931-B1 PROPYLENE BLOCK COPOLYMER JAPAN POLYPROPYLENE CORP (JP) 2018-01-24 EP disclosed
US-6916886-B2 Propylene block copolymer JAPAN POLYPROPYLENE CORPORATION (JP) 2005-07-12 US disclosed
US-20050009993-A1 Propylene block copolymer JAPAN POLYPROPYLENE CORPORATION (JP) 2005-01-13 US disclosed
EP-1454931-A1 PROPYLENE BLOCK COPOLYMER Japan Polypropylene Corporation (JP) 2004-09-08 EP disclosed
US-5817670-A RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1998-10-06 US disclosed
EP-0779292-A1 NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1997-06-18 EP disclosed
US-4895587-A Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-01-23 US disclosed
EP-0206251-B1 HALOACETAMIDE COMPOUNDS, PROCESS FOR PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDE TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1988-09-07 EP disclosed
EP-0206251-A1 Haloacetamide compounds, process for production thereof, and use thereof as herbicide TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-12-30 EP disclosed