Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886289 | 0.91 | MAPK9 (0.65) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL2420939 | 0.90 | MAPK9 (0.63) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL2425309 | 0.88 | MAPK9 (0.60) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL2422850 | 0.87 | MAPK9 (0.75) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL6439255 | 0.86 | MAPK9 (0.76) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL6438481 | 0.86 | MAPK9 (0.76) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL4972085 | 0.82 | MAPK9 (0.68) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL2420008 | 0.81 | MAPK9 (0.68) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL2420683 | 0.77 | MAPK9 (0.85) | MAPK9MAPK10MEN1KMT2AEPHX2 | |
| SCHEMBL2426655 | 0.77 | MAPK9 (0.66) | MAPK9MAPK10MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-B1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS (AN) | 2005-11-16 | — | — | EP | claimed |