Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.50 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437341 | 1.00 | TSHR (0.64) | TSHRLPAR2LPAR3LPAR1THRB | |
| SCHEMBL22444842 | 0.98 | TSHR (0.61) | TSHRLPAR2LPAR3LPAR1THRB | |
| SCHEMBL16669742 | 0.95 | TSHR (0.58) | TSHRLPAR2LPAR3LPAR1ALDH1A1 | |
| SCHEMBL15062349 | 0.93 | TSHR (0.58) | TSHRLPAR2LPAR3LPAR1THRB | |
| SCHEMBL31208246 | 0.90 | TSHR (0.80) | TSHRALOX15HSD17B10POLBAPEX1 | |
| SCHEMBL9261227 | 0.90 | TSHR (0.80) | TSHRALOX15HSD17B10POLBAPEX1 | |
| SCHEMBL16669481 | 0.90 | TSHR (0.80) | TSHRALOX15HSD17B10POLBAPEX1 | |
| SCHEMBL16669478 | 0.90 | TSHR (0.80) | TSHRALOX15HSD17B10POLBAPEX1 | |
| SCHEMBL180887 | 0.90 | TSHR (0.80) | TSHRALOX15HSD17B10POLBAPEX1 | |
| SCHEMBL180885 | 0.90 | TSHR (0.80) | TSHRALOX15HSD17B10POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897255-B1 | Latex compositions containing ethylenically unsaturated esters of long-chain alkenols and applications thereof | UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2005-05-24 | — | — | US | disclosed |
| US-6001913-A | COATINGS, ADHESIVES AND INKS FROM BLENDS OF PLASTICIZING CROSSLINKABLE ALKENOL ESTER OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACID MONOMER | THE UNIVERSITY OF SOUTHERN MISSISSIPPI | 1999-12-14 | — | — | US | disclosed |