Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 1.00 |
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | PLAU | P00749 | 1/20 | 1.00 |
| ▸ | HPN | P05981 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49000 | 1.00 | F2 (1.00) | F2F10PLAUHPN | |
| SCHEMBL7426564 | 1.00 | F2 (1.00) | F2F10PLAUHPN | |
| SCHEMBL7444271 | 1.00 | F2 (1.00) | F2F10PLAUHPN | |
| SCHEMBL7438024 | 0.98 | F2 (1.00) | F2F10PLAUHPN | |
| Hydrochloric Acid SCHEMBL4904976 | 0.98 | F2 (0.97) | F2F10PLAUHPN | |
| SCHEMBL7442529 | 0.98 | F2 (1.00) | F2F10PLAUHPN | |
| Hydrochloric Acid SCHEMBL4904982 | 0.98 | F2 (0.97) | F2F10PLAUHPN | |
| SCHEMBL7435108 | 0.98 | F2 (1.00) | F2F10PLAUHPN | |
| SCHEMBL7433726 | 0.98 | F2 (1.00) | F2F10PLAUHPN | |
| Hydrochloric Acid SCHEMBL30566763 | 0.98 | F2 (0.97) | F2F10PLAUHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633381-A | ANTICOAGULANTS | BERLEX LABORATORIES, INC. | 1997-05-27 | — | — | US | claimed |
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042287-A1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | Aventis Pharma Deutschland GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033800-A1 | INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-07-08 | — | — | WO | disclosed |
| US-5633381-A | ANTICOAGULANTS | BERLEX LABORATORIES, INC. | 1997-05-27 | — | — | US | disclosed |