Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | PREP | P48147 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360953 | 0.86 | CA12 (0.44) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6437156 | 0.86 | CA12 (0.38) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6804163 | 0.83 | CA12 (0.40) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6434922 | 0.83 | CA12 (0.36) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL5360774 | 0.82 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL5360778 | 0.82 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6433948 | 0.82 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6433944 | 0.82 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL5363897 | 0.82 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6499011 | 0.82 | CA12 (0.39) | CA12CA1CA9PREPHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1317425-B1 | RESORCINOL DERIVATIVES | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1165495-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000056702-A1 | RESORCINOL DERIVATIVES | PFIZER INC. (US) | 2000-09-28 | — | — | WO | disclosed |