SCHEMBL6437545

SCHEMBL6437545

CN(C)c1cccc([Al])c1N(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
GAA P10253 4/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 4/20 0.35
TSHR P16473 3/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
NSD2 O96028 1/20 0.35
EGFR P00533 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
CHEK1 O14757 1/20 0.34
NEK2 P51955 1/20 0.34
LIMK1 P53667 1/20 0.34
DYRK1A Q13627 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
MCL1 Q07820 1/20 0.34
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5639919 0.73 MAPT (0.46) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL1955056 0.71 MAPT (0.44) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL4588436 0.71 MAPT (0.44) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL2099550 0.71 MAPT (0.44) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL3787606 0.71 MAPT (0.44) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL816506 0.71 MAPT (0.44) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL8966974 0.71 MAPT (0.44) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL5516037 0.71 MAPT (0.40) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL9757011 0.70 GAA (0.39) MAPTGAAKDM4EALDH1A1TSHR
SCHEMBL15657124 0.70 MAPT (0.43) MAPTGAAKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1238989-B1 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS INC (JP) 2015-10-07 EP disclosed
US-6897176-B2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2005-05-24 US disclosed
US-20020169072-A1 Olefin polymerization catalyst and process for produing Olefin polymer with the catalyst MITSUI CHEMICALS, INC. (JP) 2002-11-14 US disclosed
EP-1238989-A2 Olefin polymerization catalyst and process for producing olefin polymer with the catalyst Mitsui Chemicals, Inc. (JP) 2002-09-11 EP disclosed