Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339287 | 1.00 | ABCB1 (0.55) | ABCB1SPPL2A | |
| SCHEMBL4339286 | 1.00 | ABCB1 (0.55) | ABCB1SPPL2A | |
| SCHEMBL6437591 | 1.00 | ABCB1 (0.55) | ABCB1SPPL2A | |
| SCHEMBL4345123 | 0.93 | ABCB1 (0.58) | ABCB1SPPL2A | |
| SCHEMBL4345120 | 0.93 | ABCB1 (0.58) | ABCB1SPPL2A | |
| SCHEMBL4340245 | 0.91 | ABCB1 (0.54) | ABCB1SPPL2A | |
| SCHEMBL4340247 | 0.91 | ABCB1 (0.54) | ABCB1SPPL2A | |
| SCHEMBL4348423 | 0.90 | ABCB1 (0.54) | ABCB1SPPL2A | |
| SCHEMBL4348420 | 0.90 | ABCB1 (0.54) | ABCB1SPPL2A | |
| SCHEMBL4345687 | 0.90 | ABCB1 (0.51) | ABCB1SPPL2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878728-B1 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICAL INCORPORATED (US) | 2005-04-12 | — | — | US | disclosed |