SCHEMBL643765

SCHEMBL643765

CC#Cc1cc[c]cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28519940 0.85 CYP1A1 (0.61)
SCHEMBL11883827 0.82 APP (0.44)
SCHEMBL3913662 0.78 CYP1A1 (0.65)
SCHEMBL5496457 0.74 GRM5 (0.50)
SCHEMBL238995 0.74 APP (0.70)
SCHEMBL28515756 0.73 CYP1A1 (0.47)
SCHEMBL5958174 0.72
SCHEMBL13006866 0.72 CYP2A6 (0.55)
SCHEMBL5958075 0.72
SCHEMBL16288648 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217457-A 4-amino-1H-pyrrole compound, preparation method and application 中国药科大学 2023-06-06 CN claimed
CN-114080384-B Herbicidal cyclohexanedione derivatives 先正达农作物保护股份公司 2024-07-12 CN disclosed
EP-4373865-A1 CATALYTIC HYDROGENOLYSIS OF A POLYMER Northwestern University (US) 2024-05-29 EP disclosed
WO-2024089225-A1 PROCESS FOR THE SYNTHESIS OF METHOXY SUBSTITUTED BENZALDEHYDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-05-02 WO disclosed
CN-113896607-B Olefin oligomerization process using a catalyst comprising a chromium complex having a phosphacycle-containing ligand 陶氏环球技术有限责任公司 2024-04-16 CN disclosed
CN-117651723-A Catalytic hydrogenolysis of polymers 西北大学 2024-03-05 CN disclosed
US-11896965-B2 Chromium complex and catalyst therefrom DOW GLOBAL TECHNOLOGIES LLC (US) 2024-02-13 US disclosed
CN-113402538-B Fluorescent molecule taking quinolinium ions as framework and labeled polypeptide or protein thereof and preparation method 香港理工大学深圳研究院 2023-12-19 CN disclosed
WO-2023213926-A1 CHEMICAL PROCESS SYNGENTA CROP PROTECTION AG (CH) 2023-11-09 WO disclosed
CN-112955422-B polycyclic compound 三菱瓦斯化学株式会社 2023-08-22 CN disclosed
US-6617324-B1 Phenyl, cyclohexyl and pyridinyl or pyrimidinyl-substituted G. D. SEARLE & COMPANY 2003-09-09 US disclosed
US-20030105096-A1 Serotonin transport inhibitors WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) 2003-06-05 US disclosed
US-6525059-B1 Mitogen-activated protein kinases (MAP); G. D. SEARLE & COMPANY 2003-02-25 US disclosed
US-6514977-B1 For treating p38 kinase mediated disorders G.D. SEARLE & COMPANY 2003-02-04 US disclosed
US-6423713-B1 Substituted pyrazoles as p38 kinase inhibitors G. D. SEARLE & COMPANY 2002-07-23 US disclosed
EP-1144403-A1 SUBSTITUED PYRAZOLES AS P38 KINASE INHIBITORS G.D. SEARLE & CO. (US) 2001-10-17 EP disclosed
EP-1142857-A1 PROCESSES FOR PRODUCING ACRYLIC ACID DERIVATIVE NIPPON SODA CO., LTD. (JP) 2001-10-10 EP disclosed
CN-1061657-C Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient MITSUI TOATSU CHEMICALS (JP) 2001-02-07 CN disclosed
WO-2000031063-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. SEARLE & CO. (US) 2000-06-02 WO disclosed
CN-1146993-A Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient MITSUI TOATSU CHEMICALS (JP) 1997-04-09 CN disclosed