Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Binapacryl SCHEMBL54301 | 0.93 | TDP1 (0.68) | TDP1ALDH1A1LMNAKMT2APOLB | |
| Binapacryl SCHEMBL29609584 | 0.93 | TDP1 (0.68) | TDP1ALDH1A1LMNAKMT2APOLB | |
| Binapacryl SCHEMBL27879188 | 0.92 | TDP1 (0.67) | TDP1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL14906 | 0.91 | TDP1 (1.00) | TDP1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL29413979 | 0.91 | TDP1 (1.00) | TDP1ALDH1A1LMNAKMT2APOLB | |
| Hydrogen Sulfide SCHEMBL28307249 | 0.90 | TDP1 (0.98) | TDP1ALDH1A1LMNAKMT2APOLB | |
| Formic Acid SCHEMBL15401615 | 0.89 | TDP1 (0.91) | TDP1ALDH1A1LMNAKMT2APOLB | |
| Binapacryl SCHEMBL6102052 | 0.86 | TDP1 (0.60) | TDP1ALDH1A1LMNAKMT2APOLB | |
| Binapacryl SCHEMBL28214156 | 0.83 | TDP1 (0.57) | TDP1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL28083815 | 0.82 | TDP1 (0.79) | TDP1ALDH1A1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109169678-A | Bactericide and composition thereof | 侨昌现代农业有限公司 | 2019-01-11 | — | — | CN | disclosed |
| WO-2005051617-A2 | ANTIFUNGAL PRESERVATIVE COMPOSITION FOR AN ENVIRONMENTALLY FRIENDLY PROCESS | MICROBES UNLIMITED, LLC (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050112393-A1 | Antifungal preservative composition for an environmentally friendly process | MICROBES UNLIMITED, LLC | 2005-05-26 | — | — | US | disclosed |
| EP-0929217-B1 | SORDARIN DERIVATIVES | MERCK & CO INC (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1007031-B1 | 4-CYANO-4-DEFORMYLSORDARIN DERIVATIVES | MERCK & CO INC (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-0938307-B1 | SORDARIN AND DERIVATIVES THEREOF FOR USE AS CROP ANTIFUNGAL AGENTS | MERCK & CO INC (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-1007032-B1 | 4-CYANO-4-DEFORMYLSORDARICIN DERIVATIVES | MERCK & CO INC (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2003007878-A2 | ANTIFUNGAL AGENTS OF SORDARIN DERIVATIVES | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |
| US-6436395-B1 | Rosellinia subiculata ATCC 74386 and fungus ATCC 74387 for producing sordarin compounds for fungi control | MERCK & CO., INC. | 2002-08-20 | — | — | US | disclosed |
| EP-1007032-A4 | 4-CYANO-4-DEFORMYLSORDARICIN DERIVATIVES | MERCK & CO INC (US) | 2002-03-27 | — | — | EP | disclosed |
| US-6040463-A | FUNGICIDE | MERCK & CO., INC. (US) | 2000-03-21 | — | — | US | disclosed |
| EP-0929217-A4 | SORDARIN DERIVATIVES | MERCK & CO INC (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5972996-A | 4-cyano-4-deformylsordarin derivatives | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5965612-A | 4-cyano-4-deformylsordaricin derivatives | MERCK & CO., INC. (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0938307-A1 | SORDARIN AND DERIVATIVES THEREOF FOR USE AS CROP ANTIFUNGAL AGENTS | Merck & Co., Inc. (US) | 1999-09-01 | — | — | EP | disclosed |
| EP-0929217-A1 | SORDARIN DERIVATIVES | Merck & Co., Inc. (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1999009975-A1 | 4-CYANO-4-DEFORMYLSORDARICIN DERIVATIVES | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1999009974-A1 | 4-CYANO-4-DEFORMYLSORDARIN DERIVATIVES | MERCK & CO., INC. (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1998015178-A1 | SORDARIN DERIVATIVES | MERCK & CO., INC. (US) | 1998-04-16 | — | — | WO | disclosed |
| WO-1998011891-A1 | SORDARIN AND DERIVATIVES THEREOF FOR USE AS CROP ANTIFUNGAL AGENTS | MERCK & CO., INC. (US) | 1998-03-26 | — | — | WO | disclosed |