SCHEMBL6438121

N=C(N)c1cccc(CNC(=O)c2cc3cc(O)ccc3n2Cc2cccc(C(=N)N)c2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	20/20	1.00

▸	F2	P00734	7/20	0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12589590	0.85	F10 (1.00)	F10F2
Iodide SCHEMBL6432604	0.85	F10 (0.98)	F10F2
Trifluoroacetic Acid SCHEMBL6432896	0.84	F10 (1.00)	F10F2
Trifluoroacetic Acid SCHEMBL6437256	0.84	F10 (1.00)	F10F2
SCHEMBL6432899	0.83	F10 (0.86)	F10F2
Acetic Acid SCHEMBL6436891	0.83	F10 (0.94)	F10F2
Trifluoroacetic Acid SCHEMBL6432891	0.83	F10 (0.96)	F10F2
Trifluoroacetic Acid SCHEMBL6439393	0.80	F10 (0.92)	F10F2
SCHEMBL12589593	0.79	F10 (1.00)	F10F2
Trifluoroacetic Acid SCHEMBL6434781	0.78	F10 (0.88)	F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1042287-B1	INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA	AVENTIS PHARMA GMBH (DE)	2005-04-20	—	—	EP	disclosed
US-6337344-B1	ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS	AVENTIS PHARMA DEUTSCHLAND GMBH (DE)	2002-01-08	—	—	US	disclosed
EP-1042287-A1	INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA	Aventis Pharma Deutschland GmbH (DE)	2000-10-11	—	—	EP	disclosed
WO-1999033800-A1	INDOLE DERIVATIVES AS INHIBITORS OR FACTOR XA	AVENTIS PHARMA DEUTSCHLAND GMBH (DE)	1999-07-08	—	—	WO	disclosed