Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.52 |
| ▸ | MEN1 | O00255 | 12/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438200 | 1.00 | MAPT (0.52) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6436712 | 0.87 | MAPT (0.57) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6436709 | 0.87 | MAPT (0.57) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6510185 | 0.87 | BIRC5 (0.50) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6435175 | 0.85 | BIRC5 (0.68) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6435171 | 0.85 | BIRC5 (0.68) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6415263 | 0.84 | MAPT (0.64) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6432656 | 0.83 | BIRC5 (0.59) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6432659 | 0.83 | BIRC5 (0.59) | MAPTMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6507696 | 0.82 | MAPT (0.52) | MAPTMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529531-A1 | Oxadiazolopyrazine derivatives as pharmaceutically active compounds | 4SC AG (DE) | 2005-05-11 | — | — | EP | disclosed |