Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 19/20 | 0.82 |
| ▸ | F2 | P00734 | 1/20 | 0.72 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.72 |
| ▸ | ELANE | P08246 | 1/20 | 0.72 |
| ▸ | CTSG | P08311 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471075 | 0.91 | CMA1 (0.77) | CMA1F2PRSS1ELANECTSG | |
| SCHEMBL6453073 | 0.90 | CMA1 (1.00) | CMA1F2PRSS1ELANECTSG | |
| SCHEMBL6459484 | 0.88 | CMA1 (0.88) | CMA1F2PRSS1ELANECTSG | |
| SCHEMBL6479887 | 0.86 | CMA1 (0.71) | CMA1F2PRSS1ELANECTSG | |
| SCHEMBL6469309 | 0.86 | CMA1 (0.68) | CMA1F2PRSS1ELANECTSG | |
| SCHEMBL6453077 | 0.83 | CMA1 (0.61) | CMA1F2PRSS1ELANECTSG | |
| SCHEMBL14196601 | 0.82 | CMA1 (0.89) | CMA1PTGS1 | |
| Moxalactam SCHEMBL49017 | 0.81 | PTGS1 (1.00) | CMA1PTGS1 | |
| Moxalactam SCHEMBL194012 | 0.81 | PTGS1 (1.00) | CMA1PTGS1 | |
| Moxalactam SCHEMBL194013 | 0.81 | PTGS1 (1.00) | CMA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005074932-A1 | THE USE OF (S) - PANTOPRAZOLE MAGNESIUM FOR THE TREATMENT OF AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2005-08-18 | — | — | WO | disclosed |
| US-20050165041-A1 | Combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-07-28 | — | — | US | disclosed |
| EP-1517706-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA Pharma AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| EP-1506016-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA Pharma AG (DE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003094967-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003094968-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |