Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.57 |
| ▸ | PPARA | Q07869 | 15/20 | 0.57 |
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473326 | 0.92 | PPARD (0.54) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3372315 | 0.89 | PPARD (0.72) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6439387 | 0.88 | PPARD (0.55) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6439572 | 0.85 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3372154 | 0.83 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3370411 | 0.82 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL3374163 | 0.81 | PPARD (0.69) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3370487 | 0.80 | PPARD (0.67) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3371253 | 0.77 | PPARD (0.50) | PPARDPPARAPPARG | |
| SCHEMBL3369920 | 0.77 | PPARD (0.70) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537091-A1 | NOVEL 2-ARYLTHIAZOLE COMPOUNDS AS PPARALPHA AND PPARGAMMA AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004020420-A1 | NOVEL 2-ARYLTHIAZOLE COMPOUNDS AS PPARALPHA AND PPARGAMA AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2004-03-11 | — | — | WO | disclosed |