SCHEMBL6438852

SCHEMBL6438852

CO[C@H]1O[C@@H]2COC(c3ccccc3)O[C@H]2[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 1.00
▸ MEN1 O00255 2/20 1.00
▸ L3MBTL1 Q9Y468 3/20 0.81
▸ ALDH1A1 P00352 4/20 0.48
▸ PKM P14618 1/20 0.39
▸ CYP3A4 P08684 2/20 0.37
▸ MAPT P10636 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ PDCD1 Q15116 3/20 0.36
▸ CD274 Q9NZQ7 3/20 0.36
▸ ADRA1A P35348 1/20 0.35
▸ GAA P10253 2/20 0.34
▸ ATM Q13315 1/20 0.34
▸ NCOA3 Q9Y6Q9 1/20 0.34
▸ USP2 O75604 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ ABCC3 O15438 1/20 0.34
▸ ABCC4 O15439 1/20 0.34
▸ TOP2A P11388 1/20 0.34
▸ TOP2B Q02880 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37187 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL4546275 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL5575995 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL16018595 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL15280759 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL12168228 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL5695275 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL20671060 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL22227398 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM
SCHEMBL4943654 1.00 KMT2A (1.00) KMT2AMEN1L3MBTL1ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10626249-B2 Polyolefin compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-21 — — US claimed
EP-3347413-B1 POLYOLEFIN COMPOSITIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-08-07 — — EP claimed
US-20190023870-A1 POLYOLEFIN COMPOSITIONS SABIC GLOBAL TECHNOLOGIOES B.V. (NL) 2019-01-24 — — US claimed
EP-3347413-A1 POLYOLEFIN COMPOSITIONS SABIC Global Technologies B.V. (NL) 2018-07-18 — — EP claimed
CN-108026340-A Polyolefin compositions SABIC环球技术有限责任公司 2018-05-11 — — CN claimed
WO-2017042092-A1 POLYOLEFIN COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-03-16 — — WO claimed
EP-1150689-A1 CHEMICAL COMPOUNDS NORSK HYDRO ASA (NO) 2001-11-07 — — EP claimed
WO-2000048609-A1 CHEMICAL COMPOUNDS NORSK HYDRO ASA (NO) 2000-08-24 — — WO claimed
JP-11323309-A — — None — — JP disclosed
US-10626249-B2 Polyolefin compositions SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-04-21 — — US disclosed
EP-3347413-B1 POLYOLEFIN COMPOSITIONS SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-08-07 — — EP disclosed
US-20190023870-A1 POLYOLEFIN COMPOSITIONS SABIC GLOBAL TECHNOLOGIOES B.V. (NL) 2019-01-24 — — US disclosed
CN-108026340-A Polyolefin compositions SABIC环球技术有限责任公司 2018-05-11 — — CN disclosed
US-9919055-B2 Sugar-linker-drug conjugates ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-03-20 — — US disclosed
US-20120148502-A1 Carbohydrate-Mediated Tumor Targeting Arizona Board of Regents, a body corporate of the State of Ariz. acting for and on behalf of Ariz. (US) 2012-06-14 — — US disclosed
WO-2011019419-A1 CARBOHYDRATE-MEDIATED TUMOR TARGETING ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2011-02-17 — — WO disclosed
US-20050077648-A1 Solution casting method and polymer film FUJIFILM CORPORATION (JP) 2005-04-14 — — US disclosed
EP-1150689-A1 CHEMICAL COMPOUNDS NORSK HYDRO ASA (NO) 2001-11-07 — — EP disclosed
WO-2000048609-A1 CHEMICAL COMPOUNDS NORSK HYDRO ASA (NO) 2000-08-24 — — WO disclosed
JP-H11323309-A GELLING AGENT COMPRISING SUGAR BENZYLIDENE DERIVATIVE JAPAN SCIENCE & TECHNOLOGY CORP 1999-11-26 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148502-A1 Carbohydrate-Mediated Tumor Targeting CA14, CA13, CA12 KMT2A 4059/4885MEN1 550/4885L3MBTL1 4040/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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