Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14595290 | 1.00 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL14202990 | 1.00 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL5044487 | 0.99 | SLC6A2 (0.98) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL5044485 | 0.99 | SLC6A2 (0.98) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL5048306 | 0.99 | SLC6A2 (0.98) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL6438236 | 0.89 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL8283440 | 0.89 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL14595288 | 0.89 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| SCHEMBL6469426 | 0.89 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL6252355 | 0.88 | SLC6A2 (0.78) | SLC6A2SLC6A4SLC6A3ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534694-A1 | ARYL AND HETEROARYL MORPHOLINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004018441-A1 | ARYL AND HETEROARYL MORPHOLINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2004-03-04 | — | — | WO | disclosed |