Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5369590 | 0.84 | TLR7 (0.58) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4152431 | 0.77 | POLB (0.45) | LMNAPOLBSMN1; SMN2ALOX15TSHR | |
| SCHEMBL9551426 | 0.75 | TLR7 (0.47) | TLR7TLR8PDE4D | |
| SCHEMBL5350042 | 0.74 | TLR7 (0.70) | TLR7TLR8 | |
| SCHEMBL4152643 | 0.74 | TLR7 (0.46) | TLR7TLR8LMNAPDE4DSMN1; SMN2 | |
| SCHEMBL2895254 | 0.71 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL22803635 | 0.71 | TLR7 (0.65) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL2888314 | 0.71 | TLR7 (0.46) | TLR7TLR8LMNAPDE4DSMN1; SMN2 | |
| SCHEMBL10734409 | 0.70 | TLR7 (0.46) | TLR7NPC1RAB9ATLR8KDM4E | |
| SCHEMBL10587197 | 0.70 | TLR7 (0.45) | TLR7NPC1RAB9ATLR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541572-A1 | Thioether substituted imidazoquinolines | 3M Innovative Properties Company (US) | 2005-06-15 | — | — | EP | disclosed |