Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6437739 | 0.94 | NPC1 (0.57) | NPC1KMT2ASMN1; SMN2NPSR1TP53 | |
| SCHEMBL6457317 | 0.86 | CYP11B1 (0.47) | NPC1KMT2AGCGRSMN1; SMN2NPSR1 | |
| SCHEMBL40667 | 0.85 | KMT2A (0.41) | NPC1KMT2ASMN1; SMN2RAB9AMAPT | |
| SCHEMBL6302225 | 0.82 | NPC1 (0.55) | NPC1KMT2ASMN1; SMN2RAB9AMAPT | |
| SCHEMBL10534461 | 0.81 | KDM4E (0.54) | KMT2AMAPTALDH1A1HPGDCYP1A2 | |
| SCHEMBL8598610 | 0.81 | KMT2A (0.57) | KMT2AMAPTALDH1A1HPGDCYP1A2 | |
| SCHEMBL16241350 | 0.81 | NPC1 (0.53) | NPC1KMT2ASMN1; SMN2NPSR1TP53 | |
| SCHEMBL10537208 | 0.81 | HPGD (0.47) | KMT2AGCGRMAPTALDH1A1HPGD | |
| SCHEMBL9856912 | 0.80 | GCGR (0.67) | NPC1KMT2AGCGRSMN1; SMN2NPSR1 | |
| SCHEMBL16919764 | 0.80 | NPC1 (0.50) | NPC1KMT2ASMN1; SMN2NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506959-A2 | Derivatised molecules for mass spectrometry | OXFORD GENE TECHNOLOGY IP LIMITED (GB) | 2005-02-16 | — | — | EP | disclosed |