Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 3/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 11/20 | 0.39 |
| ▸ | CTRC | Q99895 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440436 | 1.00 | F2 (0.43) | F2PRSS1F11RENCMA1 | |
| SCHEMBL6438997 | 0.87 | HDAC1 (0.48) | — | |
| SCHEMBL6439001 | 0.87 | HDAC1 (0.48) | — | |
| SCHEMBL6435982 | 0.84 | F2 (0.47) | F2PRSS1F11CMA1CTRC | |
| SCHEMBL6438590 | 0.84 | F2 (0.46) | F2PRSS1F11CMA1CTRC | |
| SCHEMBL6438586 | 0.84 | F2 (0.46) | F2PRSS1F11CMA1CTRC | |
| SCHEMBL6435980 | 0.84 | F2 (0.47) | F2PRSS1F11CMA1CTRC | |
| SCHEMBL6435727 | 0.83 | F2 (0.45) | F2PRSS1F11CMA1CTRC | |
| SCHEMBL6435731 | 0.83 | F2 (0.45) | F2PRSS1F11CMA1CTRC | |
| SCHEMBL6438912 | 0.82 | KCNH2 (0.45) | F2PRSS1F11CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505062-A1 | Heterocyclic derivatives and their use as antithrombotic agents | Akzo Nobel N.V. (NL) | 2005-02-09 | — | — | EP | disclosed |
| US-6432955-B1 | ANTICOAGULANTS | AKZO NOBEL N.V. (NL) | 2002-08-13 | — | — | US | disclosed |