Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.73 |
| ▸ | PPARA | Q07869 | 20/20 | 0.73 |
| ▸ | PPARD | Q03181 | 5/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446810 | 0.98 | PPARG (0.70) | PPARGPPARAPPARD | |
| SCHEMBL5562482 | 0.92 | PPARG (0.78) | PPARGPPARAPPARD | |
| SCHEMBL5562727 | 0.89 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL5557308 | 0.86 | PPARG (0.77) | PPARGPPARAPPARD | |
| SCHEMBL5563881 | 0.85 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL5558245 | 0.85 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL5564093 | 0.85 | PPARG (0.75) | PPARGPPARAPPARD | |
| SCHEMBL5557717 | 0.85 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL5759052 | 0.85 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL5763710 | 0.85 | PPARG (1.00) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572203-A1 | SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004041275-A1 | SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-21 | — | — | WO | disclosed |