Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Naphthoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.88 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.88 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.88 |
| ▸ | CDC25B | P30305 | 3/20 | 0.69 |
| ▸ | PLK1 | P53350 | 1/20 | 0.58 |
| ▸ | WDR5 | P61964 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthoic Acid SCHEMBL30401620 | 0.94 | NR4A1 (0.91) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL30233567 | 0.94 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL28110155 | 0.94 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL29352220 | 0.94 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL17258 | 0.94 | NR4A1 (1.00) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL1407017 | 0.91 | NR4A1 (0.95) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL6912565 | 0.91 | NR4A1 (0.95) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL10550060 | 0.91 | NR4A1 (0.95) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL868316 | 0.91 | NR4A1 (0.95) | NR4A1NR4A2NR4A3CDC25BPLK1 | |
| Naphthoic Acid SCHEMBL20591191 | 0.91 | NR4A1 (0.95) | NR4A1NR4A2NR4A3CDC25BPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159521-A | Amide compound and curable resin composition containing same | 尤尼吉可株式会社 | 2024-06-07 | — | — | CN | disclosed |
| CN-110398490-B | Pesticide field detection device and detection method | 中国石油大学(华东) | 2024-06-07 | — | — | CN | disclosed |
| CN-117843640-A | Ultra-low potential electrochemiluminescence carboxylesterase activity detection biosensor and kit | 河南大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117263836-A | Preparation method and application of co-reaction ligand-protected high-efficiency electrochemiluminescence gold nanocluster probe | 河南大学 | 2023-12-22 | — | — | CN | disclosed |
| EP-1215216-B1 | Cellulose ester of aromatic carboxylic acid | FUJI PHOTO FILM CO LTD (JP) | 2005-07-27 | — | — | EP | disclosed |
| EP-1215216-A1 | Cellulose ester of aromatic carboxylic acid | FUJI PHOTO FILM CO., LTD. (JP) | 2002-06-19 | — | — | EP | disclosed |