Methane

Methane

SCHEMBL6442579

C.CC(Nc1ccccc1)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
HSD17B10 Q99714 4/20 0.52
ALDH1A1 P00352 3/20 0.52
LMNA P02545 3/20 0.52
TSHR P16473 3/20 0.52
CYP3A4 P08684 2/20 0.52
ALOX15 P16050 2/20 0.52
ALOX12 P18054 2/20 0.52
THRB P10828 1/20 0.52
RECQL P46063 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
GAA P10253 2/20 0.47
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
NAPRT Q6XQN6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33927 0.98 TDP1 (0.56) TDP1HSD17B10ALDH1A1LMNATSHR
SCHEMBL1531678 0.98 TDP1 (0.56) TDP1HSD17B10ALDH1A1LMNATSHR
SCHEMBL1330911 0.98 TDP1 (0.56) TDP1HSD17B10ALDH1A1LMNATSHR
SCHEMBL1331551 0.98 TDP1 (0.56) TDP1HSD17B10ALDH1A1LMNATSHR
SCHEMBL33928 0.98 TDP1 (0.56) TDP1HSD17B10ALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL10424136 0.96 TDP1 (0.54) TDP1HSD17B10ALDH1A1LMNATSHR
SCHEMBL7073966 0.96 TDP1 (0.54) TDP1HSD17B10ALDH1A1LMNATSHR
SCHEMBL2584998 0.96 TDP1 (0.54) TDP1HSD17B10ALDH1A1LMNATSHR
Hydrochloric Acid SCHEMBL10445714 0.96 TDP1 (0.54) TDP1HSD17B10ALDH1A1LMNATSHR
SCHEMBL7468986 0.96 TDP1 (0.54) TDP1HSD17B10ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050004288-A1 Resin composition, composition for solder resist, and cured article obtained therefrom NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2005-01-06 US disclosed
EP-1416003-A1 RESIN COMPOSITION, COMPOSITION FOR SOLDER RESIST, AND CURED ARTICLE OBTAINED THEREFROM Nippon Kayaku Kabushiki Kaisha (JP) 2004-05-06 EP disclosed