Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24426792 | 0.85 | PLA2G1B (0.42) | ALDH1A1MAOB | |
| SCHEMBL16316747 | 0.77 | TDP1 (0.41) | TSHRTDP1CYP3A4CALM1IDO1 | |
| SCHEMBL1304376 | 0.76 | TSHR (0.48) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL2129272 | 0.76 | TSHR (0.48) | TSHRTDP1CALM1IDO1THRB | |
| SCHEMBL230856 | 0.74 | TDP1 (0.43) | TSHRTDP1CYP3A4CALM1IDO1 | |
| SCHEMBL10882128 | 0.74 | TDP1 (0.43) | TSHRTDP1CYP3A4CALM1IDO1 | |
| SCHEMBL4250554 | 0.74 | TDP1 (0.43) | TSHRTDP1CYP3A4CALM1IDO1 | |
| SCHEMBL14413267 | 0.73 | TDP1 (0.38) | TDP1CYP3A4ESR1ESR2CA1 | |
| SCHEMBL6442090 | 0.72 | TDP1 (0.41) | TSHRTDP1CYP3A4CES2CES1 | |
| Hydrochloric Acid SCHEMBL10899109 | 0.72 | CYP3A4 (0.41) | TSHRTDP1CYP3A4CALM1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956072-B1 | Thermoplastic resin composition and molded object thereof | POLYPLASTICS CO., LTD. (JP) | 2005-10-18 | — | — | US | disclosed |