SCHEMBL6443525

SCHEMBL6443525

CCCCCCCCCCCC(=NO)c1ccccc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 0.56
KDM4E B2RXH2 2/20 0.55
LMNA P02545 2/20 0.55
USP2 O75604 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
HTT P42858 1/20 0.55
NPC1 O15118 1/20 0.55
HSP90AA1 P07900 1/20 0.55
RAB9A P51151 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MAPT P10636 3/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
FAAH O00519 2/20 0.48
CNR1 P21554 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20342720 0.86 SMN1; SMN2 (0.54) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL7687295 0.82 MAPT (0.57) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL7687297 0.82 MAPT (0.57) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL7924687 0.81 KDM4E (0.59) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL10783627 0.81 KDM4E (0.59) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL7418674 0.81 KDM4E (0.59) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL7418675 0.81 KDM4E (0.59) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL10783630 0.81 KDM4E (0.59) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL5995590 0.81 KDM4E (0.59) MGLLKDM4ELMNAUSP2ALOX15
SCHEMBL8903696 0.81 KDM4E (0.59) MGLLKDM4ELMNAUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539873-A2 STABILLIZATION OF ORGANIC MATERIALS Ciba SC Holding AG (CH) 2005-06-15 EP disclosed
WO-2004024810-A2 STABILLIZATION OF ORGANIC MATERIALS CIBA, SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-03-25 WO disclosed