Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443667 | 0.88 | TSHR (0.43) | TSHRRECQLALDH1A1CYP3A4TDP1 | |
| SCHEMBL15819399 | 0.84 | TSHR (0.37) | TSHRRECQLCA2TP53CA1 | |
| SCHEMBL2365214 | 0.84 | TSHR (0.40) | TSHRRECQLALDH1A1CYP3A4TDP1 | |
| SCHEMBL27610479 | 0.79 | TP53 (0.43) | TSHRTP53LMNA | |
| SCHEMBL7023430 | 0.79 | TSHR (0.45) | TSHRRECQLALDH1A1CYP3A4TDP1 | |
| SCHEMBL15610478 | 0.78 | TSHR (0.39) | TSHRRECQLALDH1A1CYP3A4TDP1 | |
| SCHEMBL10618168 | 0.78 | TP53 (0.42) | TP53LMNA | |
| SCHEMBL11125680 | 0.78 | TP53 (0.42) | TP53LMNA | |
| SCHEMBL777709 | 0.76 | — | — | |
| SCHEMBL5248267 | 0.76 | RECQL (0.50) | TSHRRECQLALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050049328-A1 | Surface film with depositing function, the production and use thereof | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-03-03 | — | — | US | disclosed |