Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492146 | 0.79 | TDP1 (0.55) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL4190024 | 0.79 | TDP1 (0.55) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL29600036 | 0.72 | MAPK1 (0.61) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL14941439 | 0.72 | MAPK1 (0.61) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL28485565 | 0.71 | TDP1 (0.46) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL165195 | 0.71 | TDP1 (0.46) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL14938632 | 0.71 | MAPK1 (0.75) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL29599321 | 0.71 | MAPK1 (0.75) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL653542 | 0.70 | TAAR1 (0.32) | — | |
| SCHEMBL943471 | 0.70 | TDP1 (1.00) | TDP1MAPK1ALDH1A1L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565523-A1 | IRRADIATED, OXIDIZED OLEFIN POLYMER DISPERSING AGENTS | Basell Poliolefine Italia S.P.A. (IT) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004113440-A1 | ENGINEERING THERMOPLASTIC COMPOSITIONS CONTAINING OXIDIZED OLEFIN POLYMER DISPERSING AGENTS | BASELL POLIOLEFINE ITALIA S.P.A. (US) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004048467-A1 | IRRADIATED, OXIDIZED OLEFIN POLYMER DISPERSING AGENTS | BASELL POLIOLEFINE ITALIA S.P.A. (US) | 2004-06-10 | — | — | WO | disclosed |
| US-20040102582-A1 | Irradiated, oxidized olefin polymer dispersing agents | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-05-27 | — | — | US | disclosed |
| US-6677395-B1 | ISOTACTIC ADDITION POLYMER DISPERSANTS CONTAINING PIGMENTS, CARBON BLACK, FLAMEPROOFING, MICROBIOCIDES OR ANTACIDS MIXTURES, FOR IMPROVED VISCOSITY OR FLEXIBILITY | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2004-01-13 | — | — | US | disclosed |