⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016675 | 1.00 | — | — | |
| SCHEMBL1625646 | 1.00 | — | — | |
| Acetic Acid SCHEMBL28449373 | 0.94 | HPGD (0.47) | — | |
| SCHEMBL27530374 | 0.94 | HPGD (0.49) | — | |
| SCHEMBL2200874 | 0.94 | HPGD (0.49) | — | |
| Propionic Acid SCHEMBL28449795 | 0.89 | HPGD (0.43) | — | |
| SCHEMBL28589967 | 0.89 | — | — | |
| SCHEMBL28601788 | 0.89 | — | — | |
| SCHEMBL4914347 | 0.89 | — | — | |
| Butyric Acid SCHEMBL28457472 | 0.85 | TDP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757050-B1 | Antibacterial penem esters derivatives | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-06-04 | — | — | EP | claimed |
| EP-0757050-A1 | Antibacterial penem esters derivatives | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | claimed |
| CN-105219527-B | Tetrahydrofuran derivatives as fragrances | 西姆莱斯股份公司 | 2023-11-14 | — | — | CN | disclosed |
| EP-3452466-B1 | HETEROCYCLIC TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-08-12 | — | — | EP | disclosed |
| WO-2020081508-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-04-23 | — | — | WO | disclosed |
| US-10344247-B2 | Tetrahydrofuran derivatives as fragrances | SYMRISE AG (DE) | 2019-07-09 | — | — | US | disclosed |
| EP-3452466-A1 | HETEROCYCLIC TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | Amgen Inc. (US) | 2019-03-13 | — | — | EP | disclosed |
| US-10150760-B2 | Compounds for use in preparing heterocyclic triazole agonists of the APJ receptor | AMGEN INC. (US) | 2018-12-11 | — | — | US | disclosed |
| US-20180222895-A1 | COMPOUNDS FOR USE IN PREPARING HETEROCYCLIC TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC. | 2018-08-09 | — | — | US | disclosed |
| US-9988369-B2 | Heterocyclic triazole compounds as agonists of the APJ receptor | AMGEN INC. (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170320860-A1 | HETEROCYCLIC TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC. | 2017-11-09 | — | — | US | disclosed |
| US-20150376546-A1 | TETRAHYDROFURAN DERIVATIVES AS FRAGRANCES | SYMRISE AG (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| EP-0757050-B1 | Antibacterial penem esters derivatives | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-5885981-A | REACTING A HALOGENATED ALKYL COMPOUND WITH A PENEM COMPOUND | SUNTORY LIMITED (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5830889-A | ANTIBIOTIC IN ORAL DOSAGE FORMS | SUNTORY LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0757050-A1 | Antibacterial penem esters derivatives | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| WO-1992003442-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | disclosed |