Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442451 | 0.98 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTTSHRFOLH1ALDH1A1 | |
| Potassium SCHEMBL7927858 | 0.89 | HTT (0.44) | SMN1; SMN2HTTTSHRFOLH1ALDH1A1 | |
| Potassium Ion SCHEMBL6442452 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTTSHRFOLH1ALDH1A1 | |
| SCHEMBL2973368 | 0.84 | TSHR (0.52) | SMN1; SMN2HTTTSHRFOLH1ALDH1A1 | |
| SCHEMBL809052 | 0.82 | SLC1A1 (0.55) | TSHRFOLH1ALDH1A1SLC1A1CYP2C19 | |
| Hydrochloric Acid SCHEMBL5551687 | 0.81 | SLC1A1 (0.54) | TSHRFOLH1ALDH1A1SLC1A1CYP2C19 | |
| SCHEMBL809091 | 0.81 | SLC1A1 (0.54) | TSHRFOLH1ALDH1A1SLC1A1CYP2C19 | |
| SCHEMBL5217777 | 0.81 | CYP2C19 (0.49) | SMN1; SMN2HTTTSHRFOLH1ALDH1A1 | |
| SCHEMBL27711652 | 0.81 | CYP2C19 (0.49) | SMN1; SMN2HTTTSHRFOLH1ALDH1A1 | |
| SCHEMBL27711647 | 0.81 | CYP2C19 (0.49) | SMN1; SMN2HTTTSHRFOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1699325-A | A process for the preparation of 2-chloro-3-(phenylmethoxy)propionic acid potassium salt | BRACCO IMAGING SPA (IT) | 2005-11-23 | — | — | CN | disclosed |
| EP-1095009-B1 | A PROCESS FOR THE PREPARATION OF 4-CARBOXY- 5,8,11- TRIS(CARBOXYMETHYL)- 1-PHENYL- 2-OXA- 5,8,11- TRIAZATRIDECAN- 13-OIC ACID | BRACCO IMAGING SPA (IT) | 2005-06-15 | — | — | EP | disclosed |
| CN-1307558-A | Process for preparing 4-carboxy-5, 8, 11-tris (carboxymethyl) -1-phenyl-2-oxa-5, 8, 11-triazatridecane-13-oic acid | BRACCO IMAGING SPA (IT) | 2001-08-08 | — | — | CN | disclosed |
| EP-1095009-A2 | A PROCESS FOR THE PREPARATION OF 4-CARBOXY- 5,8,11- TRIS(CARBOXYMETHYL)- 1-PHENYL- 2-OXA- 5,8,11- TRIAZATRIDECAN- 13-OIC ACID | Bracco Imaging S.p.A. (IT) | 2001-05-02 | — | — | EP | disclosed |
| US-6162947-A | Process for the preparation of 4-carboxy-5, 8,11-tris (carboxymethyl)-phenyl-2-oxa-5, 8 11-triazatridecan | DIBRA S.P.A. (IT) | 2000-12-19 | — | — | US | disclosed |
| WO-2000002847-A2 | A PROCESS FOR THE PREPARATION OF 4-CARBOXY- 5,8,11- TRIS(CARBOXYMETHYL)- 1-PHENYL- 2-OXA- 5,8,11- TRIAZATRIDECAN- 13-OIC ACID | BRACCO S.P.A. (IT) | 2000-01-20 | — | — | WO | disclosed |