Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.95 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.95 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3612928 | 1.00 | KCNA5 (0.95) | KCNA5SCN5ASLC18A2SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1762334 | 0.99 | KCNA5 (0.93) | KCNA5SCN5ASLC18A2SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1762369 | 0.99 | KCNA5 (0.93) | KCNA5SCN5ASLC18A2SIGMAR1L3MBTL1 | |
| SCHEMBL6807137 | 0.98 | KCNA5 (1.00) | KCNA5SCN5ASLC18A2SIGMAR1L3MBTL1 | |
| SCHEMBL12391697 | 0.98 | KCNA5 (1.00) | KCNA5SCN5ASLC18A2SIGMAR1L3MBTL1 | |
| SCHEMBL2624914 | 0.98 | KCNA5 (1.00) | KCNA5SCN5ASLC18A2SIGMAR1L3MBTL1 | |
| SCHEMBL12203898 | 0.88 | KCNA5 (0.82) | KCNA5SCN5ASLC18A2SIGMAR1 | |
| SCHEMBL2625053 | 0.88 | KCNA5 (0.82) | KCNA5SCN5ASLC18A2SIGMAR1 | |
| SCHEMBL12391704 | 0.82 | KCNA5 (1.00) | KCNA5SCN5ASLC18A2SIGMAR1 | |
| SCHEMBL10207927 | 0.82 | KCNA5 (1.00) | KCNA5SCN5ASLC18A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979685-B1 | Cycloalkyl amine compounds and uses thereof | CARDIOME PHARMA CORP. (CA) | 2005-12-27 | — | — | US | claimed |